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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89a33b92fac2816e4d0b125914c24734ade423e47e34bc626bbc0455693a614c' 
  AND token = 'IQcWLAEvmNvUrmjaBqEJTcXFz8N3sCCAPVtzPPrwXds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}