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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7613eeb072c01f136ce215bbf495a85fdaa8c498cccbef30b7a9fa5ec1f49bef' 
  AND token = 'j2V8vLZb4iSn/rQZQNM7kLB0eTRwNYXp/p50Uz/tbaU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}