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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35126756cec417d339fe5452d07baa24f97a768b639c3e640ee626a6ed095489' 
  AND token = 'tMFZOz09OoHtrz1DnK4wvnWzT9ddirRbk/mm1muqH0c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}