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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fcc850bbe49c261b8309cc15b69a3721a9d9f8facc4d620691fc8521164c99a' 
  AND token = 'ty4U4qirt7naWpyq3/BaoonrYjsARHShAX7OIT+JMd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}