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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de0fd603f36c4cea1f72c298e439a2ccaca77b002a2473ab2e4eee1b4330d76b' 
  AND token = 'PuNay1mjITAJPnybpGTfQrt0rUgq/scVbpsab347p/w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}