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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd29591ce729128420fe989f064e4a1258baee2028fb326f18322faed9ca4dc79' 
  AND token = '4cifgJS4kdfg/pbgMFxRhSyptAid1I+MWE9/486Pid8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}