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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ab4f22fca9a05a711b86c401b313c3654307ba2fcb2639e5b080de088fc646e' 
  AND token = 'OFE8kBnVl1XibzSnbUXh5ACPm2QahsNUamstAfoWI7A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}