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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c552676466d7629fbe1623bd8f981a44836909f944603fc9347306ef536e739a' 
  AND token = 'P0D0Kiclph0fg8ILYnxwsBQTrN7i5IS2/xApYoAKcRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}