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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2480c2e3da53383c40ee1a6ed1d7c850a396db0c942593662203f86d87a63d2' 
  AND token = 'U4JhS8IeSu1rSoaF3IZOnzdevUdYKfPZIcCHseHnrlI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}