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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd54aaec0b50b7d2714622a57b1f4e67d5396d1472f8c2d99f18d6e52032ba636' 
  AND token = 'Orma9zkZ7UBhD8KmXezJIyaEyKKoJUJWx1sHeCoC0N0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}