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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29fd8a4e992aead49d7b8c01659f93c7c2187b527b6a2629bbe4702c40e0c644' 
  AND token = '85IXOruouMBnMUXdIumI9zSBJQnU4hj9xPLiOuiisiM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}