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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d05a45086dd52f535ad3312c0fa926b1f198c2aab82c34d0bb7213080358d50' 
  AND token = '/2DEjITM00HIh/phQ+G2ISMQ0bgu1ql6rYqp0QfFAWM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}