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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d3fa5f2de231d0e9f71d93f7354edf79a29756e59fd90d30505052f44116b50' 
  AND token = 'zPssBMi5t7DkpptTqmQJNKEJ+36SFJK8Ilo9Cd4EQSE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}