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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03f232c27b40f8a226b9d43e6e080dc3e008a09426f0ef3eefe2bb369fdc6453' 
  AND token = 'HExsOz+buTjngWX+7iibXPS16cMk3Pugz+serM/Yomg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}