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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de0074b5fa4b408588c9f981677fbec07c0a1d78f5a7239644b748550be02f2a' 
  AND token = 'yzJ0/jAvmyLL+8PNBGFOk//8Wt4IUkyIhGuZxk9m0ow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}