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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a05eeb2794a89f556f7d5fb49e31ca03412b1150399f5e6ecf52f288c791dcf4' 
  AND token = 'ZlzAoa+H+k3y3BvBRrnn687eXbgUJSf2THDOJbnYL1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}