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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc0cf1e25921c6c7bd0ebe515b1f26afdabf98076e5f47f308f87df8e9213727' 
  AND token = 'YI8x7z5WCnAevr3QP/nDVhG2xC/NLYwNxR8BQjMsPx0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}