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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d229cc7714ac4c1dd336cf4b7d97a1cce30ee765b17f81988a830124e42df9a' 
  AND token = 'VQlPnLXkZljdZxmoGVEO3qjcYNtGbZcOr3jcGUJ8t7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}