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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b10d8945d6c87cd05f2e2105e29f6d610a3cb8a6832b6aaea3a21d313c620b4' 
  AND token = 'PPJdpFUHsCIrZTu4V90CksSY3fH8Befm3C5VMpLd6jU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}