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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '94a98452bcc59f8778cd4c0ef191774cb92a6e1b57b0d1b6a8a234cc7c9d6dce' 
  AND token = 'MRBGxpST55RB/Kz4nETDOKI3x6WW0uhkeFq4VrSKubM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}