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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36525ff89e4a47c8797d8f15e70a4f17b85e8f262862d0826f91f618bdd99cfb' 
  AND token = 'roycLqaGrsaTqVL9qqHJhcltNRf0t/vprEj82FY7Cps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}