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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc8ea2d2d6acedfa0950a0572d752d5e5102eb596ef69323d719e172e29bc0ba' 
  AND token = '319LvJoHK206uVQC8PI/2IqBYCBzA0xAlK5bPsSQ8DY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}