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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a04007d0e827d9d383100d3654b73015f7a03d58651bbca3e1c9fb102c7b5dbb' 
  AND token = '6D7PTRSdvkrMtsdGoTtzpSa0NmUEq7x7ZmYtKA9OZvc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}