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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a94a17f4b3cfcdd1199b48cb6fa53f091a238f13d255f4489a3f4b9c494502b' 
  AND token = '0Empqr6FkHQrjnAF5TiP8fGW496btd5XAF5XXTydo9w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}