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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8eb42039978c93bffcde8af785fa4fd91f9c77ef6d07c3cc6ddbf692de943633' 
  AND token = '4MsewyW7gnEKpAjrjQ5zIPXSNa7AD/KMWPlN6qy1Jg4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}