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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b6e4f5649e8977accd04a12c7514e0903fc603789983b3b7922a63482be8afa' 
  AND token = 'U0XALyFo7JL/Scj8CbdeSBqMb2JkEgpJIMr6moQ2fI8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}