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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3a93874ed22a964a8e9c37430317b782007f1d54cd5e0650c4081d2d75006e2' 
  AND token = 'bU6aaDmusUiIeqNZkMoZh4XkzNKtBHEFZ0Ynsk42Ecc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}