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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e29fd93b8d76e9e806c19a4ee49a9a852d9f4cad714d113cb094e2cf78dfa0d7' 
  AND token = 'mAfcvbzCrYeDt8hg+fznMzbRhar8ZHJ8kvrQNrm2Gjs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}