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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce2f954818f7bc9aeb8f19d92c5ce23e36464e2746db66c6d12216340ff8e29e' 
  AND token = '2Uu7K8sdUL1sf29WLBF16KiXA/CHiQ79jAsXHcpccf8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}