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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85c35f94b825f5a78e3cf1f635153c306e0ee170ad2dec3cb9b448be918405d3' 
  AND token = 'b42o4S32MSD5NPwdgJgs5DDwJJjmohEObOSUx+n0LBo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}