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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21fa1f84bcabfb6acb97e5a710af4624213659d426d1f7c2f399628a234c5fcf' 
  AND token = 'o+kOju3CArN/DxVJHaSGAakBAk+Va+wirqe8kkNpX0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}