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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '882205fd7ae4cdf4c0ec0f72bff5c22b77336602c15f127f78c26678a385e9ca' 
  AND token = 'eyu2mwCtHUVq1ZbDOkAIY/8sN/MjuA8hlw0rK3EV7SE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}