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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edefe0e18eb46e053e292a0b0e4f4ee1d1edba1dee6608640a08e45713c5f69d' 
  AND token = 'vz3v6YjkBlMGDhG/GHq55swWshtdp79iwvWqNEwNTfk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}