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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5c782d88d7ccd0dfdbd749312ca7f3313e22a054321f46c5c8b6346904809d3' 
  AND token = 'RGFBv/6bI7A9DSFC0xTiHy2cvlgpnPYmQgnHaF2I0LY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}