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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e03fb78d99bec40be68b828966fe88e40cd4454890f6a74294052cf5aa46162' 
  AND token = 'cT0K/7C3KUIBBZ9TH8g2FaWVibvRI+xUWEvVJeN9hJg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}