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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '174b4a5e8f94ef686173cdb3e4a7ca30ea4c297c7c1c9213237c60b2fd13398c' 
  AND token = '8krhVF7PCIRP8YKlmFtzHuNtiFhge509dmF4uHCIzpA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}