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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '84eabe2b240ee37275ec4e990c44ea4dc85354ffc62380b41dd86bc900458439' 
  AND token = 'w4py4bZ84lBUZpp4+WZelJov+cryJ/dnnZhblZRVmSU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}