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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c0c9b0ba06abc21b1de44755ddb4869e2e315ea022928e6dca3070fb3314400' 
  AND token = '3n1h8DMONbhwZdCfOgd0Rqv4iK4Yyf3tAAQK8yMfp48=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}