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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e5737cb941741ea2fd28a47cdf383d13407ed03fe40e5c78991c9d23cfc1b06' 
  AND token = 'bHuULyJefvoxb3dOix+Dy/sAhoZXuITTp9UI30cZrWI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}