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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6aad021722ce43fe4c6d99b5ef22909f4dc33501fb09fa56147ec83fe8fd6c82' 
  AND token = 'm4WFx8xaIjSlrHkFqfplOnE9Ky8n8mRpzPIEgwt7i/s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}