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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c137ab615730294c4a91047c4f3660c78f33927487f38d85c7a15e9298442f3e' 
  AND token = 'FHYKU+zwd7utxKBjhw5txTiS03AzwxkK89x2cMtCDZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}