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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0ff7e6c7f4d9ef8f6a4681ba557a38f249ac2cb7d343c532ca958a580806418' 
  AND token = 'D1xnfeq4/49Im1hs3KWapqanUZxWxtuueBLbdh3913U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}