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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '395f5bb5bcd5dd39dcf71ef01967fc3787a1c0732a3159231fbe8a24560a4255' 
  AND token = 'Qi07paUFdQCbg9eSU9VfloOe5XStlCeL2S07jxiUdy4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}