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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7de5b9a3a38d40d791551bdf8163fc758cb37da752a55a06ac3f887c46ef059' 
  AND token = 'NkndWh96NBDk0Ee2jU+PMIe8Ka0eSRMlVJ5biatGOPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}