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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fb31d2c09a01b1534f98980e88b590434e77a9f08c50527e2c15382d0becb1f' 
  AND token = 'upMCBh8+DgwDS2O7JHs/8KNuNRS1Lp1pF+H+gDZzTj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}