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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6e242034e5bbb9c253aafe3dbea5506d2bd02c560304c558797f4ca71244457' 
  AND token = 'rjDW+Ufa/NcQ539GY/KC8EbtP8hjPQ4UFa2o/T/mzeM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}