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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '050f9aab0bf48bd585783a6c61ee08f4168481aa014eca39e77de76395e21ea1' 
  AND token = '0+k6Z48aCpSlhD2bvaNHqO79ehEZ2b7gXH/iqzroC2U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}