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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd203ceae0af33740213718fae2b91b097a2d2e0e58cc7ddaaa68fa3f39bfff26' 
  AND token = 'xsKkeUN+DSs8hhOiHDAeRWt9oQ3m7IQpwMFYEPIIUcM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}