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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2592b516412a55fcea90bc64ec389ff23ea79e3630f0a8cd9c135a7e920bc344' 
  AND token = 'o0CJ+3JbDKQ8PncI7RT4ebdBARmCtGtxQTbt0jiU4W0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}