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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8588dff9aefa1086b2b77fdfa9a4812535f662638c677d0261504b923c17747' 
  AND token = 'BIYWBWc+IxDBMD2A/GuehkIW1bNMhA3qS6gOETuPGb0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}